OTC VP 40% - Oxytetracycline Hydrochloride (400 mg/g)

OTC VP 40% - Oxytetracycline hydrochloride (400 mg/g)
Oral powder (WS)
Calves, pigs, poultry, fish.
STATEMENT OF THE ACTIVE SUBSTANCE (S) AND OTHER INGREDIENTS
1 g of oral powder (WS) contains:
Active substance: Oxytetracycline hydrochloride 400 mg
Excipients: Sucrose.
INDICATIONS
Treatment of infections caused by microorganisms sensitive to oxytetracycline
- calves: infections of the respiratory tract (Mycoplasma spp.) and gastrointestinal system (E. coli)
- pigs: respiratory tract infections, gastrointestinal tract infections.
- poultry: respiratory infections (Mycoplasma spp., E.coli and CRD), gastrointestinal tract infections
(fowl cholera caused by Pasteurella multocida).
- fish (trout and carp): infections caused by Aeromonas salmonicida (trout furunculosis, carp
erythrodermatitis).
CONTRAINDICATIONS
It should not be given to animals with known hypersensitivity to tetracyclines. It is not given to
animals with impaired liver and kidney function.
ADVERSE REACTIONS
Drug overdose or longer duration of therapy, and sometimes the use of recommended
therapeutic doses can cause indigestion accompanied by diarrhea and vomiting, and in young
animals, bone growth and tooth discoloration. Allergic reactions are also possible. In case of
hypersensitivity reaction, use antihistamines and corticosteroids.

DOSAGE FOR EACH SPECIES, ROUTES AND METHOD OF ADMINSITRATION
Poultry: 50-100 mg oxytetracycline / kg b.w. (equivalent to 12.5-25 g of OTC VP 40% oral powder per 100 kg bw or 500 g of OTC VP 40% oral powder / 1000 L drinking water), for 5-7 days.
Calves: the recommended daily dose is 20 mg oxytetracycline / kg bw. or 5g of oral powder OTC VP 40% per 100 kg bw, divided into two doses, for 5-7 days.
Pigs: The recommended daily dose is 20-30 mg of oxytetracycline / kg bw, or 5g - 7.5 g of OTC VP 40% oral powder per 100 kg bw, divided into two doses, for 5-7 days.
Fish: 20 g of oral powder (eq. 8 g of oxytetracycline) per 100 kg of fish, for 4 days. If necessary, continue the therapy for another 4 days if the death does not stop.
ADVICE ON CORRECT ADMINISTRATION
The medicine should be dissolved in a small amount of drinking water, and then mixed with the total predicted amount of water. Do not expose the drug solution prepared in this way to sunlight.
Prepare a fresh solution daily. Do not mix with milk or milk substitutes.
Fish: Mix the previously measured amount of medicine first in a small amount of the daily meal for fish, and then mix well with the rest of the food.
Due to the homogeneity of the mixture, it is important to mix in dry conditions. When mixing with pelleted food, a smaller amount of edible oil should be added to improve the adhesion of the drug to the pellet surface.
WITHDRAWAL PERIOD
Meat and offal:
Pigs: 5 days
Calves: 8 days
Poultry: 7 days,
Poultry: eggs 5 days
Fish (trout and carp): 720 ° D (degrees of the day).
SPECIAL STORAGE PRECAUTIONS
Keep out from the reach of children
Store in original package at temperature of 25oC,
Shelf life: 3 years
Shelf life after first opening 28 days
Shelf life after dilution: 24 hours, at temperatures up to 25 ̊C.
After mixing with food (fish): use immediately.

SPECIAL WARNINGS
It is not given to hens laying eggs.
Due to the increasing development of resistance to tetracyclines, it is recommended to make an antibiogram for isolated microorganisms before using the drug. The most common are resistant bacteria from the genera Proteus, Pseudomonas, as well as some strains of E.coli, Salmonella spp., Enterococcus

Special precautions to be taken by the person administering the veterinary medicinal product to animals
Persons sensitive to tetracyclines should not participate in the preparation of the drug.
Oxytetracycline (rarely) can cause contact dermatitis and therefore direct contact of the drug with the skin and mucous membranes, ie eyes, should be avoided. When working, use a harness (protective suits, gloves, masks and goggles). Hands should be washed after each contact with the drug.
SPECIAL PRECAUTIONS FOR THE DIPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS IF ANY
Any unused veterinary medicinal product or waste materials derived form such veterinary medicinal product should be disposed in accordance with local requirements.