Frontline Combo

Frontline Combo Cat, 1 antiparasitic pipette

• Used in the treatment and prevention of flea (Ctenocephalides spp.) and tick (Rhipicephalus spp., Dermatocentor spp., Ixodes spp.) infestations in cats.
• Treatment and control of flea allergic dermatitis in cats.
• Prevention of flea breeding by stopping the development of eggs, larvae and pupae developed from eggs laid by fleas for 6 weeks after application.
• Prevention and treatment of lice infestations in cats. 

Presentation:

• is a treatment that kills fleas and ticks through contact of the parasite with the medicine applied to the skin of your pet. 
• After application, it does not pass into the animal's blood, but concentrates in the sebum of its skin (a fine surface layer) and is thus stored in the sebaceous glands. It is therefore characterized by being stored for several weeks after application, being resistant to rain, baths and shampoos.
• Respecting an interval of 48 hours between application and exposure to water, and without exceeding one bath and shampoo per week, FRONTLINE remains effective even after bathing and shampooing.
• Fleas and ticks are killed when they come into contact with the insecticidal molecule on your animal's skin. It acts on the nervous system of the parasites, which die due to nervous hyperexcitation. FRONTLINE provides additional security against fleas: it also contains an insect reproduction regulator. This regulator prevents the infestation of the home with eggs laid before the flea dies.

Mode of action of the product:
On fleas

• kills adult fleas within 24 hours of their arrival on the animal. FRONTLINE Combo offers double security: it also prevents the contamination of the home with flea eggs and larvae.

On ticks

• eliminates over 90% of ticks within 48 hours of their attachment to the cat, thus reducing the risk of disease transmission. This risk is maximum after 48 hours of the tick attaching to the animal.

On animal lice

• kills lice present on the animal within a maximum of 48 hours.

Composition: 1 pipette contains

• Fipronil 50.00 mg;
• S – methoprene 60.00 mg;
• Butylhydroxyanosol 0.10 mg;
• Butylhydroxytoluene 0.05 mg;
• Ethanol 39.50 mg;
• Excipient q.sp 0.50 ml

Pharmaceutical form:

• Solution for cutaneous application.

Contraindications:

• The product should not be used in cats under 8 weeks of age or weighing less than 1 kg.
• Do not use in sick animals (systemic diseases, fever) or convalescent.
• Do not use in rabbits, as it may cause adverse reactions and even death of the animal.

Adverse effects:

• Slight hypersalivation in case of accidental ingestion of the product into the oral cavity.
• In exceptional cases, skin reactions may occur at the site of application of the product (skin discoloration, local alopecia, pruritus, erythema). Itching and general alopecia have been reported after use. In exceptional cases, hypersalivation, reversible neurological reactions (agitation, depression, nervousness), vomiting, or respiratory symptoms have been reported.
• Do not exceed the recommended dose.

Pharmaceutical precautions:

• It is very important to ensure that the product is applied in an area where the cat cannot lick the product and also to ensure that the animals do not lick each other after treatment.
• The animal should not be bathed for 2 days after treatment.
• There may already be a single tick on the animal. For this reason, the transmission of an infectious disease cannot be excluded.

Use during pregnancy: Frontline COMBO pipettes for cats can be used in pregnant and lactating cats.
Administration and dosage: The minimum interval between treatments is 4 weeks.
Route of administration: Externally, by application to the skin.
Dosage: Apply a 0.5 ml pipette to the skin in the area between the shoulder blades.
Method of administration:

1. Remove the pipette from the packaging and break the end at the pre-cut part.

2. Remove the hair to apply directly to the skin.

3. Place the tip on the skin between the animal's 2 shoulders and press the pipette several times to empty all the contents into one or two points

Overdose (symptoms, emergency procedures, antidotes)

The fur may take on a sticky appearance in the application area when more than one dose is applied.
If this phenomenon occurs, it will disappear within 24 hours after treatment.
Precautions: Avoid spraying into the animal's eyes.
Recommendations for the person administering the treatment:

This product may cause irritation of the mucous membranes and eyes. Consequently, contact of the product with the mouth or eyes should be avoided.
Animals and people with hypersensitivity to insecticides or alcohol should avoid contact with Frontline COMBO Cat pipettes.
Avoid contact with fingers; if this happens, wash hands with soap and water.
If accidentally sprayed in the eyes, it is recommended to wash with water.
Wash hands thoroughly with soap and water after applying the treatment
Avoid handling the animal until the place where the product was applied is dry, and children should not play with the animals until the fur is dry.
Therefore, it is recommended to apply the treatment in the evening, and during the night the kittens should sleep alone, not with one of the owners and especially not with children.
Do not smoke, eat or drink during the treatment.