Anprovit C 500

QUALITATIVE AND QUANTITATIVE COMPOSITION
1 kg of product contains the active substance: L-Ascorbic Acid 500 g
Excipients: up to 1000 g
PHARMACEUTICAL FORM
Powder for oral use.
CLINICAL PARTICULARS
Target species
Birds, swine
Indications for use
- To balance temperature stress (either too high or too low), transport stress, shelter stress due to the formation of new groups of animals, diet changes, vaccinations, viral diseases, parasites;
- To reduce the problems of umbilical hemorrhage in piglets;
- To improve absorption and use iron, selenium and chromium, but also to adjust copper absorption;
- To maintain the integrity of the skin and avoid breaking the fragile blood vessels under the skin;
- To reduce irritation of the respiratory mucosa due to dust, non-specific asthmatic forms, infections - especially viral ones;
- To balance the stress factors by inducing primary heart failure in pigs, caused especially by sunstroke;
- To enhance and accelerate the healing of wounds, caused by bites or surgical interventions;
- To contribute to the immune response, especially during vaccination;
- To contribute to the reduction of adverse reactions;
- To develop the characteristics and quality of carcasses for slaughter.

Contraindications
Does not exist.

Special precautions for use in animals
Does not exist.

Special precautions to be taken by the person administering the veterinary medicinal product to animals
Avoid direct contact with the product while handling it.

Adverse reactions (frequency and severity)
Does not exist.

Use during pregnancy, lactation or egg laying
It does not cause problems.

Interactions with other medicinal products or other forms of interactions
The simultaneous use of acetylsalicylic acid with other acids from the NSAID class (non-steroidal and anti-inflammatory) can cause stomach irritation. Large doses of ascorbic acid can increase blood levels of acetylsalicylic acid and other medicinal or antibiotic acids such as tetracyclines.

Quantities to be administered and route of administration
Swine.
• Up to 60 kg g.v.: 0.80 g AnproVitC 500/10 kg g.v.
• Over 60 kg g.v.: 0.60 g AnproVitC 500/10 kg g.v.
Birds
• Stress caused by high temperatures, laying hens in the laying period, stress
caused by handling or others: 6.0-12.0 g Anpro VitC 500/100 liters drinking water or 10.0-20.0 g/100 kg feed (equivalent to 10-15 mg ascorbic acid/kg g.w.), for at least 3 days after remission symptoms;
• Stress caused by vaccination or beak cutting, sunstroke and hypothermia or
others: 12.0-20.0 g Anpro VitC 500/100 liters of drinking water or 20.0-35.0 g/100 kg of feed (equivalent to 15-20 mg ascorbic acid/kg b.w.), for at least 3 days after remission of symptoms;
• Parasitic diseases, infections: 30.0 g Anpro VitC 500/100 liters of drinking water or 40.0-60.0 g/100 kg of feed (equivalent to 30-40 mg ascorbic acid/kg b.w.), for at least 3 days after remission of symptoms;
• Stress caused by transport: 100.0 g Anpro VitC 500/100 liters of drinking water for 24 hours or 150.0-200.0 g/100 kg of feed for 24 hours (100-120 mg ascorbic acid/kg b.w.).

Route of administration: oral, well mixed in drinking water or feed.
Instructions for correct administration: The product must be administered every 12 hours or administered continuously through an automatic dispenser.

Waiting time
0 days.

PHARMACOLOGICAL PROPERTIES
L-ascorbic acid is a biologically active substance that has been identified as a distinguishing factor of fresh fruits and vegetables, able to prevent the onset of scurvy in humans. L-ascorbic acid is synthesized naturally (birds and pigs) in sufficient doses for normal physiological requirements. In special physiological moments of the lifespan of animal species of zootechnical interest, a rapid intake and high consumption of L-ascorbic acid is necessary. The main mechanism of action of ascorbic acid is based on reducing the oxidation potential, depending on this it can reduce metals. This allows the acid to take part in many hydroxylation reactions, important for metabolism. L-ascorbic acid is much more effective when administered with bioflavonoids, calcium and magnesium. In order to develop its antioxidant function, it should be administered together with other biological antioxidants, which ensure a strong synergism between them, especially with Vitamin E.
L-ascorbic acid is distributed in all animal tissues; no proteins were found that would create any specific connection with it. In all species, the metabolic process begins with the reversible conversion of ascorbic acid into dihydroascorbic acid. In general, the acid that is absorbed is eliminated through urine, sweat and feces. Acid excretion through urine depends on the reserves present in the body, on the amount from which it is taken and on the kidney functions.

PHARMACEUTICAL PARTICULARS
List of excipients
Colloidal silicate
Dextrose